Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 1.00 |
| ▸ | BCHE | P06276 | 10/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.75 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146771 | 0.89 | BCHE (1.00) | ACHEBCHESIGMAR1CHRM4 | |
| SCHEMBL3147014 | 0.80 | BCHE (1.00) | ACHEBCHESIGMAR1CHRM4 | |
| SCHEMBL3157204 | 0.78 | BCHE (1.00) | ACHEBCHEHTR1ACHRM4 | |
| SCHEMBL8133153 | 0.78 | BCHE (0.63) | ACHEBCHESIGMAR1HTR1A | |
| SCHEMBL3137160 | 0.74 | BCHE (0.75) | ACHEBCHESIGMAR1HTR1ACHRM4 | |
| SCHEMBL7240526 | 0.74 | SIGMAR1 (1.00) | ACHEBCHESIGMAR1 | |
| SCHEMBL3155847 | 0.73 | ACHE (1.00) | ACHEBCHECHRM4 | |
| SCHEMBL3137141 | 0.72 | ACHE (1.00) | ACHEBCHECHRM4 | |
| SCHEMBL9793444 | 0.72 | OPRM1 (0.77) | ACHEBCHESIGMAR1CHRM4 | |
| SCHEMBL7368234 | 0.72 | SIGMAR1 (0.74) | ACHEBCHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758888-B1 | BUTYRYLCHOLINESTERASE SELECTIVE INHIBITORS | NEUROPHARMA S A U (ES) | 2010-02-17 | — | — | EP | disclosed |
| US-20080119521-A1 | Butyrlcholinesterase Selective Inhibitors | NEUROPHARMA, S.A. (ES) | 2008-05-22 | — | — | US | disclosed |
| US-20080119521-A1 | Butyrlcholinesterase Selective Inhibitors | NEUROPHARMA, S.A. (ES) | 2008-05-22 | — | — | US | disclosed |
| US-20080119521-A1 | Butyrlcholinesterase Selective Inhibitors | NEUROPHARMA, S.A. (ES) | 2008-05-22 | — | — | US | disclosed |
| CN-1960986-A | Butyrylcholinesterase selective inhibitors | NEUROPHARMA S A U (ES) | 2007-05-09 | — | — | CN | disclosed |
| EP-1758888-A1 | BUTYRYLCHOLINESTERASE SELECTIVE INHIBITORS | Neuropharma S.A.U. (ES) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005118570-A1 | BUTYRYLCHOLINESTERASE SELECTIVE INHIBITORS | NEUROPHARMA, S.A. (ES) | 2005-12-15 | — | — | WO | disclosed |
| EP-1600447-A1 | Butyrylcholinesterase selective inhibitors | Neuropharma S.A.U. (ES) | 2005-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119521-A1 | Butyrlcholinesterase Selective Inhibitors | BCHE, ACHE, BACE1 | ACHE 2/4885BCHE 1/4885SIGMAR1 2952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.