Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENTPD5 | O75356 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31536076 | 0.85 | ENTPD5 (1.00) | ENTPD5ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL30628881 | 0.85 | ENTPD5 (1.00) | ENTPD5ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL26760685 | 0.81 | ENTPD5 (0.65) | ENTPD5ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL6785183 | 0.80 | ENTPD5 (0.61) | ENTPD5ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL6786875 | 0.80 | ENTPD5 (0.61) | ENTPD5ALDH1A1CYP3A4CYP2C9TSHR | |
| Strongylophorine-24 SCHEMBL31571162 | 0.73 | ENTPD5 (0.76) | ENTPD5ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL25060244 | 0.73 | ALDH1A1 (0.68) | ENTPD5ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL9572259 | 0.73 | ALDH1A1 (1.00) | ENTPD5ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL83395 | 0.73 | ALDH1A1 (1.00) | ENTPD5ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL1096342 | 0.73 | ALDH1A1 (1.00) | ENTPD5ALDH1A1CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122146-A1 | COMPOUNDS FOR REDUCING NEUROINFLAMMATION | THE SCRIPPS RESEARCH INSTITUTE | 2025-04-17 | — | — | US | claimed |
| US-20250122146-A1 | COMPOUNDS FOR REDUCING NEUROINFLAMMATION | THE SCRIPPS RESEARCH INSTITUTE | 2025-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122146-A1 | COMPOUNDS FOR REDUCING NEUROINFLAMMATION | HSF1, HSPA2, KEAP1 | ENTPD5 4851/4885ALDH1A1 1692/4885CYP3A4 4685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.