SCHEMBL31540199

SCHEMBL31540199

O=C(O)C(=O)c1ccc(C2(c3ccc(O)cc3)CCOCC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPT1B Q92523 1/20 0.56
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
CES2 O00748 1/20 0.42
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA3 P07451 1/20 0.37
TYR P14679 1/20 0.37
DRD1 P21728 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
RXRA P19793 1/20 0.35
PTPRC P08575 3/20 0.35
PTPN1 P18031 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31540183 0.83 ESR2 (0.64) ESR1ESR2CA12CA1CA2
SCHEMBL1257287 0.80 ESR2 (0.55) ESR1ESR2CA12CA1CA2
SCHEMBL31540186 0.76 ADORA3 (0.39) CA12CA1CA9RXRAPTPRC
SCHEMBL593133 0.75 CPT1B (1.00) CPT1BESR1ESR2CES2CA12
SCHEMBL31540169 0.75 ESR2 (0.53) ESR1ESR2MAPTTDP1HDAC1
SCHEMBL9043671 0.73 CPT1B (0.95) CPT1BESR1ESR2CES2CA12
SCHEMBL31540171 0.73 ALDH1A1 (0.35) RXRAPTPRCPTPN1PTPN2MAPT
SCHEMBL3811364 0.69 ESR2 (0.80) ESR1ESR2CA12CA1CA2
SCHEMBL7530533 0.69 ESR2 (0.80) ESR1ESR2CA12CA1CA2
Bicarbonate SCHEMBL8524990 0.69 ESR1 (0.83) ESR1ESR2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684303-A Heterocyclic compound of difunctional degradable androgen receptor and application thereof 上海超阳药业有限公司 2025-03-25 CN disclosed