SCHEMBL593133

SCHEMBL593133

O=C(O)C(=O)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPT1B Q92523 1/20 1.00
CES2 O00748 2/20 0.68
CA1 P00915 3/20 0.62
CA2 P00918 3/20 0.62
CA12 O43570 2/20 0.62
CA7 P43166 2/20 0.62
CA9 Q16790 2/20 0.62
CA14 Q9ULX7 2/20 0.62
CA3 P07451 1/20 0.62
TYR P14679 1/20 0.62
DRD1 P21728 1/20 0.62
CA4 P22748 1/20 0.62
CA6 P23280 1/20 0.62
CA5A P35218 1/20 0.62
CA5B Q9Y2D0 1/20 0.62
MAPT P10636 3/20 0.57
LMNA P02545 2/20 0.57
ESR1 P03372 1/20 0.57
ESR2 Q92731 1/20 0.57
PKM P14618 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9043671 0.97 CPT1B (0.95) CPT1BCES2CA1CA2CA12
SCHEMBL7611819 0.88 CPT1B (0.78) CPT1BCES2SRD5A2PTPN1PTPRC
SCHEMBL181662 0.85 CES2 (0.79) CPT1BCES2CA1CA2CA12
Hydrochloric Acid SCHEMBL29249310 0.85 CPT1B (0.74) CPT1BCES2SRD5A2PTPN1PTPRC
SCHEMBL31540211 0.83 CPT1B (0.69) CPT1BCES2CA1CA2CA12
Acetic Acid SCHEMBL16816910 0.81 CES2 (0.73) CPT1BCES2CA1CA2CA12
SCHEMBL2370346 0.81 CES2 (1.00) CPT1BCES2CA1CA2CA12
SCHEMBL2302999 0.80 CPT1B (0.67) CPT1BCES2CA1CA2CA12
SCHEMBL2441056 0.80 TSHR (0.71) CPT1BCES2CA1CA2CA12
SCHEMBL11139630 0.79 CPT1B (0.65) CPT1BCES2CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558329-B2 Methods and compositions for treating 4-hydroxyphenylpyruvate dioxygenase-like (HPDL)-related diseases or disorders NEW YORK UNIVERSITY (US) 2026-02-24 US claimed
US-12497364-B2 Compound for the determination of the protein FKBP12 and a sensor unit comprising it UNIVERSITA DEGLI STUDI DI FIRENZE (IT) 2025-12-16 US claimed
CN-118908819-B Preparation method of organic ketone compound under synergistic catalysis of light and metal 延安大学 2025-04-18 CN claimed
CN-118908819-A Preparation method of organic ketone compound under synergistic catalysis of light and metal 延安大学 2024-11-08 CN claimed
US-20240130987-A1 METHODS AND COMPOSITIONS FOR TREATING 4- HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE (HPDL)-RELATED DISEASES OR DISORDERS NEW YORK UNIVERSITY (US) 2024-04-25 US claimed
CN-115851645-A Proteobacterium vulgaris meso-diaminopimelate dehydrogenase mutant and application thereof 江南大学 2023-03-28 CN claimed
US-20230033380-A1 A COMPOUND FOR THE DETERMINATION OF THE PROTEIN FKBP12 AND A SENSOR UNIT COMPRISING IT UNIVERSITA DEGLI STUDI DI FIRENZE (IT) 2023-02-02 US claimed
EP-4077280-A1 A COMPOUND FOR THE DETERMINATION OF THE PROTEIN FKBP12 AND A SENSOR UNIT COMPRISING IT Universita' Degli Studi di Firenze (IT) 2022-10-26 EP claimed
WO-2021124269-A1 A COMPOUND FOR THE DETERMINATION OF THE PROTEIN FKBP12 AND A SENSOR UNIT COMPRISING IT UNIVERSITÀ DEGLI STUDI DI FIRENZE (IT) 2021-06-24 WO claimed
CN-111056890-A Method for preparing aryl ketone by free radical-free radical coupling reaction of ketoacid decarboxylation and fatty aldehyde decarbonylation based on iron catalysis 湘潭大学 2020-04-24 CN claimed
EP-0599819-A2 Additives enhancing topical actions of therapeutic agents Van Scott, Eugene J., Dr. (US) 1994-06-01 EP claimed
EP-0374651-B1 PROCESS FOR THE PREPARATION OF L-PHOSPHINOTHRICINE HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-29 EP claimed
US-5004754-A Biofungicidal composition UNIVERSITE LAVAL (CA) 1991-04-02 US claimed
EP-0374651-A1 Process for the preparation of L-phosphinothricine HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP claimed
EP-0315786-A1 Process for the preparation of a d-alfa-amino acid from the corresponding alfa-keto acid STAMICARBON B.V. (NL) 1989-05-17 EP claimed
EP-0273202-A2 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. Van Scott, Eugene J., Dr. (US) 1988-07-06 EP claimed
EP-0047693-B1 PROCESS FOR THE PREPARATION OF HYDROXYARYLGLYOXYLIC ACIDS AND THEIR ALKALI SALTS, AND THEIR USE IN THE PREPARATION OF SODIUM-PARA-HYDROXYPHENYL GLYOXYLATE SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) 1984-02-15 EP claimed
WO-1982000821-A1 PROCESS FOR THE PRODUCTION OF HYDROXYARYLGLYOXYLIC ACIDS AND OF THE ALCALINE SALTS THEREOF,AND ITS APPLICATION TO THE PRODUCTION OF SODIUM PARA-HYDROXYPHENYLGLYOXYLATE SCHOUTEETEN A 1982-03-18 WO claimed
EP-0047693-A1 Process for the preparation of hydroxyarylglyoxylic acids and their alkali salts, and their use in the preparation of sodium-para-hydroxyphenyl glyoxylate SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) 1982-03-17 EP claimed
US-4110166-A CULTIVATION, CARBOXYLIC ACID FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1978-08-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558329-B2 Methods and compositions for treating 4-hydroxyphenylpyruvate dioxygenase-like (HPDL)-related diseases or disorders HPD, PGD, SLC25A11 CPT1B 86/4885CES2 1373/4885CA1 2829/4885
US-12497364-B2 Compound for the determination of the protein FKBP12 and a sensor unit comprising it FKBP14, FKBP5, FKBP1A CPT1B 3193/4885CES2 1767/4885CA1 169/4885
US-20230033380-A1 A COMPOUND FOR THE DETERMINATION OF THE PROTEIN FKBP12 AND A SENSOR UNIT COMPRISING IT FKBP14, FKBP1A, FKBP5 CPT1B 3241/4885CES2 2224/4885CA1 231/4885
US-20240130987-A1 METHODS AND COMPOSITIONS FOR TREATING 4- HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE (HPDL)-RELATED DISEASES OR DISORDERS HPD, CYP27B1, CYP27A1 CPT1B 54/4885CES2 2662/4885CA1 4158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.