Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MST1R | Q04912 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.37 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542290 | 0.91 | KDM1A (0.33) | ALKKDM1ABRD1BRPF1 | |
| SCHEMBL31542285 | 0.86 | ALK (0.40) | ALKTLR9TLR7 | |
| SCHEMBL31542299 | 0.86 | ALK (0.33) | ALKTLR9TLR7 | |
| SCHEMBL31542328 | 0.86 | GRM2 (0.35) | ALKEGFRRETIGF1RPDGFRB | |
| SCHEMBL31542292 | 0.86 | NOTCH1 (0.36) | ALKRETSIGMAR1 | |
| SCHEMBL31542324 | 0.84 | HTR1A (0.34) | ALKEGFRRETIGF1RPDGFRB | |
| SCHEMBL31542240 | 0.83 | DDB1 (0.34) | ALKEGFRRETIGF1RPDGFRB | |
| SCHEMBL31542280 | 0.80 | GPR6 (0.35) | KDM1ABRPF1 | |
| SCHEMBL31542350 | 0.79 | GPR119 (0.40) | ALKRET | |
| SCHEMBL31542294 | 0.77 | DRD2 (0.37) | ALKBRD1BRPF1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025062330-A1 | HETEROCYCLIC COMPOUNDS AS CBP SELECTIVE DEGRADERS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-03-27 | — | — | WO | disclosed |