Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRD1 | O95696 | 2/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.33 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.33 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542319 | 0.87 | ALK (0.35) | ALKBRD4BRD1BRPF1BRD9 | |
| SCHEMBL31542270 | 0.84 | BRPF1 (0.34) | ALKBRD4BRD1BRPF1BRD9 | |
| SCHEMBL31542290 | 0.83 | KDM1A (0.33) | ALKBRD4BRD1BRPF1BRD9 | |
| SCHEMBL31542279 | 0.83 | BRPF1 (0.35) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL31542332 | 0.83 | EGLN2 (0.44) | EGLN2 | |
| SCHEMBL31542330 | 0.82 | FFAR4 (0.35) | ALKBRPF1 | |
| SCHEMBL29471259 | 0.82 | BRPF1 (0.39) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL26548588 | 0.82 | BRPF1 (0.39) | BRD4BRD1BRPF1BRD9BRPF3 | |
| SCHEMBL31542335 | 0.79 | SLC6A5 (0.39) | — | |
| SCHEMBL31542278 | 0.77 | ALK (0.37) | DRD2DRD3ALKBRD1BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025062330-A1 | HETEROCYCLIC COMPOUNDS AS CBP SELECTIVE DEGRADERS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-03-27 | — | — | WO | disclosed |