Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | DGKI | O75912 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TNK1 | Q13470 | 2/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542330 | 0.90 | FFAR4 (0.35) | ALDH1A1MAPTLMNAFFAR4PARP1 | |
| SCHEMBL31542307 | 0.85 | SLC6A5 (0.39) | SLC6A5SLC6A9ALDH1A1KMT2AMAPT | |
| SCHEMBL31542233 | 0.81 | CRBN (0.36) | FFAR4PARP1ADRA1DADRA1AADRA1B | |
| SCHEMBL31542294 | 0.79 | DRD2 (0.37) | — | |
| SCHEMBL31542276 | 0.79 | SLC6A9 (0.35) | SLC6A5SLC6A9ALDH1A1KMT2AMAPT | |
| SCHEMBL31542319 | 0.77 | ALK (0.35) | ALDH1A1FFAR4GAA | |
| SCHEMBL31542332 | 0.74 | EGLN2 (0.44) | ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL31542270 | 0.74 | BRPF1 (0.34) | ALDH1A1 | |
| SCHEMBL31542280 | 0.74 | GPR6 (0.35) | ALDH1A1PARP1ADRA1DADRA1AADRA1B | |
| SCHEMBL31542279 | 0.73 | BRPF1 (0.35) | ALDH1A1FFAR4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025062330-A1 | HETEROCYCLIC COMPOUNDS AS CBP SELECTIVE DEGRADERS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-03-27 | — | — | WO | disclosed |