SCHEMBL3150842

SCHEMBL3150842

CC1=Cc2cccc(-c3ccc4ccccc4c3)c2C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.42
HDAC4 P56524 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
DHFR P00374 1/20 0.38
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
MET P08581 1/20 0.36
ADORA2A P29274 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30230061 1.00 GSTP1 (0.42) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL7867864 0.81 GSTP1 (0.39) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL3154256 0.80 PDCD1 (0.38) ALDH1A1HPGDHSD17B10CYP2A6
SCHEMBL20165781 0.78 BRD9 (0.35) ACHE
SCHEMBL8170273 0.77 GSTP1 (0.43) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL29785055 0.77 GSTP1 (0.53) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL3155099 0.76 HTR7 (0.40) SLC6A3ALDH1A1CYP1A2CYP3A4HPGD
SCHEMBL29776182 0.76 HTR7 (0.40) SLC6A3ALDH1A1CYP1A2CYP3A4HPGD
SCHEMBL3156085 0.76 ALDH1A1 (0.41) SLC6A2ALDH1A1CYP1A2CYP3A4HPGD
SCHEMBL29776120 0.76 HTR1A (0.44) ALDH1A1CYP1A2HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476776-B Composite catalyst composition, preparation method thereof and polyolefin prepared by using same 韩华石油化学株式会社 2022-11-25 CN disclosed
US-11267917-B2 Hybrid catalyst composition, preparation method therefor, and polyolefin prepared using same HANWHA CHEMICAL CORPORATION (KR) 2022-03-08 US disclosed
CN-109415451-B High density ethylene polymer using supported hybrid metallocene catalyst and method for preparing the same 韩华化学株式会社 2021-10-22 CN disclosed
US-10975173-B2 High-processability high-density ethylene-based polymer using hybrid supported metallocene catalyst, and preparation method therefor HANWHA CHEMICAL CORPORATION (KR) 2021-04-13 US disclosed
US-10954321-B2 High-density ethylene-based polymer using supported hybrid metallocene catalyst, and manufacturing method therefor HANWHA CHEMICAL CORPORATION (KR) 2021-03-23 US disclosed
US-10934375-B2 High-density ethylene-based polymer using hybrid supported metallocene catalyst, and preparation method HANWHA CHEMICAL CORPORATION (KR) 2021-03-02 US disclosed
US-20190169325-A1 HIGH-DENSITY ETHYLENE-BASED POLYMER USING SUPPORTED HYBRID METALLOCENE CATALYST, AND MANUFACTURING METHOD THEREFOR HANWHA CHEMICAL CORPORATION (KR) 2019-06-06 US disclosed
US-20190169323-A1 HIGH-PROCESSABILITY HIGH-DENSITY ETHYLENE-BASED POLYMER USING HYBRID SUPPORTED METALLOCENE CATALYST, AND PREPARATION METHOD THEREFOR HANWHA CHEMICAL CORPORATION (KR) 2019-06-06 US disclosed
EP-3492498-A1 HIGH-PROCESSABILITY HIGH-DENSITY ETHYLENE-BASED POLYMER USING HYBRID SUPPORTED METALLOCENE CATALYST, AND PREPARATION METHOD THEREFOR Hanwha Chemical Corporation (KR) 2019-06-05 EP disclosed
US-20190135961-A1 HYBRID CATALYST COMPOSITION, PREPARATION METHOD THEREFOR, AND POLYOLEFIN PREPARED USING SAME HANWHA CHEMICAL CORPORATION (KR) 2019-05-09 US disclosed
US-6787618-B1 TRANSPARENT, STIFF MOLDING MATERIALS; IMPACT TOUGHNESS; FOOD PACKAGING BASELL POLYPROPYLEN GMBH (DE) 2004-09-07 US disclosed
EP-0776913-B1 High molecular weight copolymers BASELL POLYOLEFINE GMBH (DE) 2004-02-04 EP disclosed
EP-1270614-A2 Copolymers containing propylene and alpha-olefin comonomer Basell Polyolefine GmbH (DE) 2003-01-02 EP disclosed
EP-0790076-B1 Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use BASELL POLYOLEFINE GMBH (DE) 2001-12-05 EP disclosed
CN-1254328-A Process for preparing substituted 2, 3-dihydro-1-indanones TARGOR GMBH (DE) 2000-05-24 CN disclosed
US-6057408-A CATALYTIC ADDITION COPOLYMERIZATION OF PROPYLENE WITH ETHYLENE OR OLEFIN TARGOR GMBH (DE) 2000-05-02 US disclosed
EP-0576970-B1 Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts HOECHST AG (DE) 1998-01-14 EP disclosed
EP-0790076-A2 Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use HOECHST AKTIENGESELLSCHAFT (DE) 1997-08-20 EP disclosed
EP-0776913-A2 High molecular weight copolymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-06-04 EP disclosed
EP-0576970-A1 Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10975173-B2 High-processability high-density ethylene-based polymer using hybrid supported metallocene catalyst, and preparation method therefor EEF1A1, FDFT1, EEF2 GSTP1 2463/4885HDAC4 3666/4885HDAC2 3871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.