Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 4/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470815 | 0.76 | TDP2 (0.46) | TDP2PDE10ACHRM3PDE4APDE4B | |
| SCHEMBL20320451 | 0.76 | TDP2 (0.50) | TDP2PDE10ACHRM3PDE4APDE4B | |
| SCHEMBL20320448 | 0.68 | TDP2 (0.49) | TDP2PDE10ACHRM3PDE4APDE4B | |
| SCHEMBL20106957 | 0.67 | TDP2 (0.40) | TDP2AOC3 | |
| SCHEMBL6915240 | 0.66 | — | — | |
| SCHEMBL1313137 | 0.64 | SIGMAR1 (0.48) | TDP2AOC3 | |
| SCHEMBL21838383 | 0.63 | DGAT1 (0.34) | — | |
| SCHEMBL3472625 | 0.63 | TDP2 (1.00) | TDP2 | |
| SCHEMBL15269532 | 0.60 | KDM4E (0.36) | TDP2 | |
| SCHEMBL17673143 | 0.60 | MPO (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072330-A1 | KIT INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-04-03 | — | — | WO | disclosed |