Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.79 |
| ▸ | MAPT | P10636 | 5/20 | 0.79 |
| ▸ | HPGD | P15428 | 3/20 | 0.79 |
| ▸ | TP53 | P04637 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.79 |
| ▸ | GLA | P06280 | 1/20 | 0.79 |
| ▸ | GABRP | O00591 | 4/20 | 0.71 |
| ▸ | GABRD | O14764 | 4/20 | 0.71 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.71 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.71 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.71 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.71 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.71 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.71 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.71 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.71 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.71 |
| ▸ | GABRE | P78334 | 4/20 | 0.71 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277649 | 0.88 | MAPT (1.00) | CYP3A4MAPTHPGDTP53ALDH1A1 | |
| 6-Aminoflavone SCHEMBL31550004 | 0.84 | EGFR (0.82) | CYP3A4MAPTHPGDTP53ALDH1A1 | |
| 6-Aminoflavone SCHEMBL926716 | 0.84 | EGFR (0.82) | CYP3A4MAPTHPGDTP53ALDH1A1 | |
| SCHEMBL5424662 | 0.83 | CYP3A4 (0.79) | CYP3A4MAPTHPGDTP53ALDH1A1 | |
| SCHEMBL17786560 | 0.83 | GABRP (0.79) | CYP3A4MAPTHPGDTP53ALDH1A1 | |
| SCHEMBL311580 | 0.82 | TNKS (1.00) | CYP3A4MAPTHPGDTP53ALDH1A1 | |
| SCHEMBL29384142 | 0.82 | TNKS (1.00) | CYP3A4MAPTHPGDTP53ALDH1A1 | |
| SCHEMBL29677954 | 0.82 | TNKS (1.00) | CYP3A4MAPTHPGDTP53ALDH1A1 | |
| SCHEMBL4981350 | 0.81 | MAPT (0.76) | CYP3A4MAPTHPGDTP53ALDH1A1 | |
| SCHEMBL3644507 | 0.81 | LCK (1.00) | CYP3A4MAPTHPGDTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610738-B2 | Treatment of Alzheimer's Disease by combining both acetylcholinesterase inhibitory activity and antioxidant activity (by virtue of their carbamoyl and flavonoid pharmacophores) | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2003-08-26 | — | — | US | disclosed |
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | CBR3, FOS, CBR1 | CYP3A4 1040/4885MAPT 3319/4885HPGD 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.