Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096128 | 0.77 | HSD17B10 (0.46) | HSD17B10LMNACYP2A6ALDH1A1ALOX15 | |
| SCHEMBL3155192 | 0.77 | ALDH1A1 (0.39) | LMNACYP2A6ALDH1A1ALOX15HPGD | |
| SCHEMBL9499893 | 0.73 | HSD17B10 (0.42) | HSD17B10LMNACYP2A6ALDH1A1ALOX15 | |
| SCHEMBL2096460 | 0.73 | ALDH1A1 (0.45) | HSD17B10LMNACYP2A6ALDH1A1ALOX15 | |
| SCHEMBL28585831 | 0.73 | HSD17B10 (0.38) | HSD17B10LMNACYP2A6ALDH1A1ALOX15 | |
| SCHEMBL10825711 | 0.71 | HSD17B10 (0.41) | HSD17B10LMNACYP2A6ALDH1A1ALOX15 | |
| SCHEMBL28869065 | 0.70 | TSHR (0.42) | HSD17B10LMNACYP2A6ALDH1A1ALOX15 | |
| SCHEMBL8420935 | 0.70 | HSD17B10 (0.44) | HSD17B10CYP2A6ALDH1A1ALOX15HPGD | |
| SCHEMBL6404489 | 0.69 | ALDH1A1 (0.41) | HSD17B10LMNACYP2A6ALDH1A1ALOX15 | |
| SCHEMBL29429137 | 0.67 | HSD17B10 (0.73) | HSD17B10CYP2A6ALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017468-A | IMIDE-MODIFIED TERPOLYMERSSULFUR-CURED RUBBER, TIRES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-04-12 | — | — | US | claimed |
| EP-0989171-A1 | N-halothio-amide-modified elastomers and their application as adhesives for precured elastomeric substrates | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-03-29 | — | — | EP | disclosed |
| US-4017468-A | IMIDE-MODIFIED TERPOLYMERSSULFUR-CURED RUBBER, TIRES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-04-12 | — | — | US | disclosed |