SCHEMBL7978097

SCHEMBL7978097

O=CN(C=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.42
NPSR1 Q6W5P4 2/20 0.42
ALOX15 P16050 1/20 0.42
CYP2A6 P11509 1/20 0.41
KMT2A Q03164 3/20 0.40
HTT P42858 3/20 0.40
MEN1 O00255 2/20 0.40
MAOA P21397 1/20 0.39
TDP1 Q9NUW8 3/20 0.36
LMNA P02545 2/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HPGD P15428 1/20 0.36
XBP1 P17861 1/20 0.36
ALOX12 P18054 1/20 0.36
RUNX1 Q01196 1/20 0.36
ATM Q13315 1/20 0.36
CBFB Q13951 1/20 0.36
TRPM8 Q7Z2W7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28038079 0.97 ALDH1A1 (0.40) ALDH1A1NPSR1ALOX15CYP2A6KMT2A
SCHEMBL27724260 0.85 ALDH1A1 (0.36) ALDH1A1NPSR1ALOX15CYP2A6KMT2A
SCHEMBL28338827 0.81 RELA (0.57) ALDH1A1CYP2A6MAOALMNATRPM8
Benzene SCHEMBL28589541 0.79 CYP3A4 (0.50) ALDH1A1ALOX15KMT2AHTTMEN1
SCHEMBL27537068 0.79 ALDH1A1 (0.54) ALDH1A1ALOX15KMT2AHTTMEN1
SCHEMBL4595696 0.78 RAB9A (0.60) ALDH1A1KMT2AMEN1TDP1LMNA
SCHEMBL5516786 0.77 ALDH1A1 (0.42) ALDH1A1NPSR1ALOX15CYP2A6KMT2A
SCHEMBL43388 0.77 ALDH1A1 (0.42) ALDH1A1NPSR1ALOX15CYP2A6KMT2A
SCHEMBL23957555 0.73 ALDH1A1 (0.36) ALDH1A1NPSR1KMT2AHTTMEN1
SCHEMBL11729911 0.72 TSHR (0.55) ALDH1A1ALOX15KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071941-A Polyamide moulding composition and thus manufactured moulded work EMS专利股份公司 2018-12-21 CN claimed
CN-103724926-B A kind of aesthetic resin composition for improving outward appearance and preparation method thereof 上海锦湖日丽塑料有限公司 2017-11-24 CN claimed
CN-107164059-A A kind of high radiation preventing high vacuum Kuan Wen robots bearing special-purpose grease composition 广西大学 2017-09-15 CN claimed
CN-106726702-A A kind of tooth whitening products without hydrogen peroxide 广州欧诺洁个人护理用品有限公司 2017-05-31 CN claimed
CN-103124715-B The manufacture method of two (amino methyl) cyclohexanes MITSUI CHEMICALS, INC. (JP) 2015-08-19 CN claimed
CN-103124715-A Method for producing bis(aminomethyl)cyclohexanes MITSUI CHEMICALS INC 2013-05-29 CN claimed
CN-102514324-A Multilayer polymer structure SOLVAY ADVANCED POLYMERS LLC 2012-06-27 CN claimed
CN-102026880-A Synthetic resin container having excellent barrier properties YOSHINO KOGYOSHO CO LTD 2011-04-20 CN claimed
CN-1860003-B Impact-modified polyamide hollow body, manufacturing method thereof and fossil fuel driving apparatus SOLVAY ADVANCED POLYMERS LLC 2010-12-08 CN claimed
CN-101431896-A Active ingredient combinations having insecticidal properties BAYER CROPSCIENCE AG (DE) 2009-05-13 CN claimed
CN-101084117-A Multilayer polymer structure SOLVAY ADVANCED POLYMERS LLC (US) 2007-12-05 CN claimed
CN-1860003-A Impact-modified polyamide hollow body SOLVAY ADVANCED POLYMERS LLC (US) 2006-11-08 CN claimed
CN-1265034-C Preparation of polyisophthaloyl m-phenylene diamide spinning solution by using semi-continuous twin screw extruder UNIV DONGHUA (CN) 2006-07-19 CN claimed
CN-1443882-A Preparation of polyisophthaloyl m-phenylene diamide spinning solution by using semi-continuous twin screw extruder UNIV DONGHUA (CN) 2003-09-24 CN claimed
CN-1309655-A Cyclic compounds useful in treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions and preparation process MERCK PATENT GMBH (DE) 2001-08-22 CN claimed
US-5981500-A Antiparasitic agents related to the milbemycins and avermectins PFIZER INC. (US) 1999-11-09 US claimed
CN-1164421-A Use of bradykinin antagonists for the production of medicaments for the treatment of chronic fibrotic liver diseases and acute liver diseases HOECHST AG (DE) 1997-11-12 CN claimed
EP-0677054-A1 NEW ANTIPARASITIC AGENTS RELATED TO THE MILBEMYCINS AND AVERMECTINS PFIZER INC. (US) 1995-10-18 EP claimed
WO-1994015944-A1 NEW ANTIPARASITIC AGENTS RELATED TO THE MILBEMYCINS AND AVERMECTINS PFIZER LIMITED (GB) 1994-07-21 WO claimed
CN-85105066-A The production of condensed seven-membered compounds, their and application 1986-12-31 CN claimed