Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558242 | 0.85 | DGAT1 (0.42) | KDM4EGLAKMT2ARXFP1MEN1 | |
| SCHEMBL535621 | 0.81 | KDM4E (0.41) | KDM4EGLAIDO1GABRPGABRD | |
| SCHEMBL25208528 | 0.80 | KDM4E (0.44) | KDM4EGLATSHRMAPTHSD17B10 | |
| SCHEMBL25361675 | 0.78 | KDM4E (0.47) | KDM4EGLAGABRPGABRDGABRA1 | |
| SCHEMBL535620 | 0.78 | KDM4E (0.39) | KDM4EKEAP1GLANFE2L2IDO1 | |
| SCHEMBL31330687 | 0.78 | KDM4E (0.39) | KDM4EKEAP1GLANFE2L2IDO1 | |
| SCHEMBL30791054 | 0.71 | GAA (0.40) | CA1CA2CA3CA9MAPT | |
| SCHEMBL16702812 | 0.71 | GAA (0.40) | CA1CA2CA3CA9MAPT | |
| SCHEMBL30067156 | 0.70 | KEAP1 (0.46) | KDM4EKEAP1GLANFE2L2IDO1 | |
| SCHEMBL951409 | 0.69 | KEAP1 (0.50) | KDM4EKEAP1GLAKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101598-A1 | BI-CYCLIC PYRIMIDINE COMPOUNDS, METHODS AND USES THEREOF | ZENO MANAGEMENT, INC. (US) | 2025-05-15 | — | — | WO | disclosed |