Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31559321 | 0.79 | HDAC1 (0.42) | — | |
| SCHEMBL31559216 | 0.77 | CYP2D6 (0.46) | CYP2D6ALDH1A1CYP3A4TSHRUSP2 | |
| SCHEMBL31559381 | 0.77 | CYP2D6 (0.45) | CYP2D6ALDH1A1CYP3A4TSHRUSP2 | |
| SCHEMBL31559253 | 0.77 | HDAC1 (0.45) | ALDH1A1CYP3A4GAA | |
| SCHEMBL2878982 | 0.77 | SLC6A9 (0.51) | CYP2D6ALDH1A1CYP3A4TSHRSLC6A9 | |
| SCHEMBL31559176 | 0.74 | SIGMAR1 (0.35) | CYP2D6ALDH1A1SIGMAR1CYP3A4TSHR | |
| SCHEMBL31559814 | 0.72 | CYP2D6 (0.37) | CYP2D6ALDH1A1SIGMAR1CYP3A4TSHR | |
| SCHEMBL19331000 | 0.70 | PTGS2 (0.40) | CYP2D6ALDH1A1SIGMAR1CYP3A4TSHR | |
| SCHEMBL19343289 | 0.68 | CYP2D6 (0.51) | CYP2D6ALDH1A1CYP3A4TSHRSLC6A9 | |
| SCHEMBL19343573 | 0.67 | SLC6A9 (0.50) | CYP2D6ALDH1A1SIGMAR1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090514-A1 | COVALENT SARM1 INHIBITORS | NURA BIO, INC. (US) | 2025-05-01 | — | — | WO | disclosed |