Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 9/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3170710 | 0.91 | HTT (0.44) | L3MBTL1POLBNAMPTHTTLMNA | |
| SCHEMBL3155794 | 0.89 | L3MBTL1 (0.48) | L3MBTL1POLBNAMPTHTTLMNA | |
| SCHEMBL3170463 | 0.85 | ADORA3 (0.40) | L3MBTL1NAMPTADORA3NPC1RAB9A | |
| SCHEMBL3169097 | 0.83 | SMN1; SMN2 (0.45) | L3MBTL1POLBLMNAMEN1KMT2A | |
| SCHEMBL3176983 | 0.82 | ADORA3 (0.57) | L3MBTL1POLBLMNAADORA3NPC1 | |
| SCHEMBL3163156 | 0.81 | RAB9A (0.48) | L3MBTL1POLBLMNAADORA3NPC1 | |
| SCHEMBL3172697 | 0.80 | NPC1 (0.47) | L3MBTL1POLBLMNAADORA3NPC1 | |
| SCHEMBL3175775 | 0.80 | ADORA3 (0.48) | L3MBTL1POLBLMNAADORA3NPC1 | |
| SCHEMBL3170845 | 0.80 | ADORA3 (0.46) | L3MBTL1POLBHTTLMNAADORA3 | |
| SCHEMBL3165534 | 0.80 | ADORA3 (0.44) | L3MBTL1NAMPTADORA3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465631-B1 | PYRIMIDINE A2B SELECTIVE ANTAGONIST COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARM INC (US) | 2010-02-24 | — | — | EP | disclosed |