Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3151319 | 0.85 | — | — | |
| SCHEMBL3151484 | 0.80 | CHRNB2 (0.38) | — | |
| SCHEMBL3150873 | 0.80 | CYP11B1 (0.35) | CYP4A11CYP4F2 | |
| SCHEMBL3155887 | 0.79 | FFAR4 (0.36) | — | |
| SCHEMBL3137211 | 0.79 | FFAR4 (0.38) | — | |
| SCHEMBL3138316 | 0.77 | KDM1A (0.41) | — | |
| SCHEMBL3151485 | 0.77 | SLC6A9 (0.37) | — | |
| SCHEMBL3773306 | 0.76 | CYP4A11 (0.32) | CYP4A11CYP4F2 | |
| SCHEMBL3151351 | 0.75 | PTGDR2 (0.38) | — | |
| SCHEMBL6482943 | 0.74 | CYP4F2 (0.39) | CYP4A11CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |