SCHEMBL31563009

SCHEMBL31563009

CC(C)(C)OC(=O)c1c(OCc2ccccc2)cc(C2=Cc3ccccc3CC2)n2ncnc12

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 3/20 0.33
TLR7 Q9NYK1 2/20 0.33
CYP2C9 P11712 1/20 0.32
PTGER1 P34995 1/20 0.32
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
HPGD P15428 1/20 0.30
HIF1A Q16665 1/20 0.30
MRGPRX4 Q96LA9 1/20 0.30
RXRB P28702 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31563010 1.00 TLR9 (0.33) TLR9TLR7CYP2C9PTGER1POLB
SCHEMBL31563011 0.89 RXRB (0.33) PTGER1POLBSMN1; SMN2CYP19A1CYP11B1
SCHEMBL8526969 0.83 EGLN2 (0.39) CYP2C9PTGER1KDM4EALDH1A1GLA
SCHEMBL8527782 0.79 CYP2C9 (0.37) TLR9TLR7CYP2C9PTGER1POLB
SCHEMBL30599272 0.76 PPARG (0.36) TLR9TLR7CYP2C9PTGER1KDM4E
SCHEMBL8520796 0.75 NR1H2 (0.39) PTGER1
SCHEMBL8517633 0.74 PTGER1 (0.41) TLR7CYP2C9PTGER1KDM4EALDH1A1
SCHEMBL12750386 0.74 ADORA3 (0.35) TLR9TLR7CYP2C9PTGER1POLB
SCHEMBL8527666 0.71 SMN1; SMN2 (0.38) CYP2C9PTGER1POLBSMN1; SMN2KDM4E
SCHEMBL30599273 0.71 ALKBH1 (0.33) CYP2C9PTGER1KDM4EALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4578855-A1 PROLYL HYDROXYLASE INHIBITOR AND USE THEREOF Suzhong Pharmaceutical Group Co., Ltd. (CN) 2025-07-02 EP disclosed
CN-119948024-A Prolyl hydroxylase inhibitor and application thereof 苏中药业集团股份有限公司 2025-05-06 CN disclosed