Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.39 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527782 | 0.88 | CYP2C9 (0.37) | DAPK1PTGER1CYP2C9KDM4EMAPT | |
| SCHEMBL8520796 | 0.87 | NR1H2 (0.39) | EGLN2PTGER1NR1H2NR1H3 | |
| SCHEMBL8520679 | 0.86 | EGLN2 (0.43) | EGLN2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL30599272 | 0.84 | PPARG (0.36) | DAPK1PTGER1CYP2C9KDM4EMAPT | |
| SCHEMBL31563010 | 0.83 | TLR9 (0.33) | PTGER1CYP2C9KDM4EMAPTBRD4 | |
| SCHEMBL31563009 | 0.83 | TLR9 (0.33) | PTGER1CYP2C9KDM4EMAPTBRD4 | |
| SCHEMBL8517633 | 0.82 | PTGER1 (0.41) | PTGER1CYP2C9KDM4EMAPTFFAR4 | |
| SCHEMBL12750386 | 0.82 | ADORA3 (0.35) | EGLN2PTGER1CYP2C9KDM4EMAPT | |
| SCHEMBL8527666 | 0.79 | SMN1; SMN2 (0.38) | DAPK1PTGER1CYP2C9KDM4EMAPT | |
| SCHEMBL30599273 | 0.78 | ALKBH1 (0.33) | PTGER1CYP2C9KDM4EMAPTFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455381-A1 | TRIAZOLOPYRIDINE COMPOUND, AND ACTION THEREOF AS PROLYL HYDROXYLASE INHIBITOR AND ERYTHROPOIETIN PRODUCTION INDUCER | Japan Tobacco, Inc. (JP) | 2012-05-23 | — | — | EP | disclosed |