Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31563093 | 0.89 | MAPT (0.50) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL31563510 | 0.87 | NPC1 (0.50) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL31563118 | 0.85 | MAPT (0.45) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6893764 | 0.84 | MAPT (0.50) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL31563055 | 0.83 | RAB9A (0.35) | MAPTKMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL31552639 | 0.81 | KCNMA1 (0.49) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL13509390 | 0.78 | MAPT (0.33) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL10136752 | 0.78 | MAPT (0.33) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL4621411 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL4621414 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077773-A1 | NOVEL TYPE I TOPOISOMERASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊维康医药有限责任公司 | 2025-04-17 | — | — | WO | disclosed |