Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 19/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 18/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 13/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | USP2 | O75604 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485428 | 0.90 | CYP3A4 (0.66) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1426231 | 0.88 | CYP2D6 (0.64) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL21276348 | 0.87 | MGLL (0.53) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23003391 | 0.87 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL30620506 | 0.86 | GPR183 (0.52) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL19838241 | 0.84 | CYP3A4 (0.66) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL20556708 | 0.84 | ERN1 (0.56) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL20469201 | 0.83 | ACACB (0.50) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8060453 | 0.83 | CYP2D6 (0.72) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL31565336 | 0.83 | RORC (0.49) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025092695-A1 | NEW HETEROCYCLIC COVALENT INHIBITOR OF MENIN, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 成都苑东生物制药股份有限公司 | 2025-05-08 | — | — | WO | disclosed |