Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31565342 | 0.83 | CYP3A4 (0.60) | CYP2D6CYP3A4TSHRUSP2CYP1A2 | |
| SCHEMBL1426231 | 0.83 | CYP2D6 (0.64) | SCD5CYP2D6CYP3A4TSHRUSP2 | |
| SCHEMBL21276348 | 0.82 | MGLL (0.53) | RORCCYP2D6CYP3A4TSHRUSP2 | |
| SCHEMBL30620506 | 0.81 | GPR183 (0.52) | RORCSCD5CYP11B2CYP2D6CYP3A4 | |
| SCHEMBL21711129 | 0.81 | CYP11B2 (0.53) | ACACBSCD5CYP11B2CYP2D6CYP3A4 | |
| SCHEMBL20469135 | 0.81 | CYP11B2 (0.53) | ACACBSCD5CYP11B2CYP2D6CYP3A4 | |
| SCHEMBL20556708 | 0.81 | ERN1 (0.56) | RORCCYP2D6CYP3A4TSHRCYP1A2 | |
| SCHEMBL20468833 | 0.80 | RORC (0.47) | ACACBRORCSCD5CYP11B2CYP2D6 | |
| SCHEMBL20468832 | 0.79 | CYP11B2 (0.52) | ACACBRORCSCD5CYP11B2CYP3A4 | |
| SCHEMBL19838241 | 0.78 | CYP3A4 (0.66) | CYP2D6CYP3A4TSHRUSP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200048267-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-13 | — | — | US | disclosed |
| WO-2018141984-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2018-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048267-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | ACACB 639/4885RORC 4866/4885SCD5 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.