Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301210 | 1.00 | CYP3A4 (0.35) | CYP3A4TDP1PDE4BPDE4APDE4C | |
| SCHEMBL31566365 | 1.00 | CYP3A4 (0.35) | CYP3A4TDP1PDE4BPDE4APDE4C | |
| SCHEMBL21042094 | 0.91 | MCL1 (0.33) | — | |
| SCHEMBL9466974 | 0.89 | — | — | |
| SCHEMBL301193 | 0.85 | TUBB1 (0.37) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1043212 | 0.84 | CNR1 (0.35) | SMN1; SMN2 | |
| SCHEMBL6414073 | 0.84 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL1043812 | 0.83 | HSD11B1 (0.30) | — | |
| SCHEMBL31566348 | 0.83 | HSD11B1 (0.30) | — | |
| SCHEMBL1224812 | 0.83 | ACHE (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096445-A1 | SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF MACROCYCLIC COMPOUNDS | ALKERMES, INC. (US) | 2025-05-08 | — | — | WO | claimed |