Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566365 | 1.00 | CYP3A4 (0.35) | CYP3A4TDP1PDE4BPDE4APDE4C | |
| SCHEMBL31566366 | 1.00 | CYP3A4 (0.35) | CYP3A4TDP1PDE4BPDE4APDE4C | |
| SCHEMBL21042094 | 0.91 | MCL1 (0.33) | — | |
| SCHEMBL9466974 | 0.89 | — | — | |
| SCHEMBL301193 | 0.85 | TUBB1 (0.37) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1043212 | 0.84 | CNR1 (0.35) | SMN1; SMN2 | |
| SCHEMBL6414073 | 0.84 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL1043812 | 0.83 | HSD11B1 (0.30) | — | |
| SCHEMBL31566348 | 0.83 | HSD11B1 (0.30) | — | |
| SCHEMBL1224812 | 0.83 | ACHE (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840116-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-HYDROXY-ALPHA-AMINOCARBOXYLIC ACID DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2012-10-03 | — | — | EP | claimed |
| US-7781609-B2 | Process for producing optically active β-hydroxy-α-aminocarboxylic acid derivative | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-24 | — | — | US | claimed |
| US-20080139825-A1 | Process For Producing Optically Active Beta-Hydroxy-Alpha-Aminocarboxylic Acid Derivative | NISSAN CHEMICAL INDUSTRIAL, LTD. (JP) | 2008-06-12 | — | — | US | claimed |
| EP-1840116-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-HYDROXY-ALPHA-AMINOCARBOXYLIC ACID DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2007-10-03 | — | — | EP | claimed |
| EP-1650207-B1 | Process for producing optically active 3-quinuclidinols | TAKASAGO PERFUMERY CO LTD (JP) | 2007-06-27 | — | — | EP | claimed |
| US-6583312-B2 | Catalytic hydrogenation of trimethylpyruvic acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-24 | — | — | US | claimed |
| US-20020035271-A1 | Process for preparing oprtically active trimethyllactic acid and its ester | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | US | claimed |
| EP-3489213-B1 | COMPOSITION FOR USE IN A METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2021-04-28 | — | — | EP | disclosed |
| US-10450261-B2 | Method for the homogeneous catalytic reductive amination of carbonyl compounds | BASF SE (DE) | 2019-10-22 | — | — | US | disclosed |
| EP-3302795-B1 | METHOD FOR THE HOMOGENEOUS CATALYTIC REDUCTIVE AMINATION OF CARBONYL COMPOUNDS | BASF SE (DE) | 2019-07-31 | — | — | EP | disclosed |
| EP-3199513-B1 | PROCESS FOR PRODUCING ALCOHOL ANALOGUE | TAKASAGO PERFUMERY CO LTD (JP) | 2019-05-08 | — | — | EP | disclosed |
| EP-3233778-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2019-02-20 | — | — | EP | disclosed |
| US-10029968-B2 | Process for producing alcohol analogue | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2018-07-24 | — | — | US | disclosed |
| US-5581007-A | Process for preparing optically active allophenylnorstatin derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0729939-A2 | Process for preparing optically active allophenylnorstatin derivatives, and intermediates for use therein | Takasago International Corporation (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5412109-A | Process for preparing optically active 4-methyl-2-oxetanone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0635004-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-25 | — | — | EP | disclosed |
| US-5306834-A | Catalytic hydrogenation of 4-methylene-2-oxetanone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0580336-A1 | Process for preparing optically active 4-methyl-2-oxetanone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-01-26 | — | — | EP | disclosed |
| WO-1993021156-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139825-A1 | Process For Producing Optically Active Beta-Hydroxy-Alpha-Aminocarboxylic Acid Derivative | HCAR2, HCAR1, ALDH7A1 | CYP3A4 207/4885TDP1 4714/4885PDE4B 3131/4885 |
| US-20020035271-A1 | Process for preparing oprtically active trimethyllactic acid and its ester | ME1, OPRK1, OPRM1 | CYP3A4 57/4885TDP1 4552/4885PDE4B 1782/4885 |
| US-10450261-B2 | Method for the homogeneous catalytic reductive amination of carbonyl compounds | CAT, AOC1, CYCS | CYP3A4 732/4885TDP1 3952/4885PDE4B 3837/4885 |
| US-10029968-B2 | Process for producing alcohol analogue | ADH1A, ADH1C, ADH5 | CYP3A4 523/4885TDP1 4077/4885PDE4B 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.