Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25346478 | 1.00 | EGFR (0.33) | EGFRMAOB | |
| SCHEMBL197752 | 0.85 | ITGB2 (0.36) | MAOB | |
| SCHEMBL18862586 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL18797086 | 0.77 | ABCC9 (0.33) | — | |
| SCHEMBL21752368 | 0.75 | ACHE (0.35) | — | |
| SCHEMBL27631611 | 0.73 | HTR2A (0.33) | EGFRMAOB | |
| SCHEMBL29661294 | 0.73 | MAPT (0.35) | — | |
| SCHEMBL17040763 | 0.73 | — | — | |
| SCHEMBL17041206 | 0.73 | MAPT (0.35) | — | |
| SCHEMBL21752292 | 0.71 | LMNA (0.39) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212994-A | Pyrazolopyrazine compounds as SHP2 inhibitors | 建新公司 | 2024-12-27 | — | — | CN | disclosed |
| EP-4448526-A1 | PYRAZOLOPYRAZINE COMPOUNDS AS SHP2 INHIBITORS | GENZYME CORPORATION (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114954-A1 | PYRAZOLOPYRAZINE COMPOUNDS AS SHP2 INHIBITORS | GENZYME CORPORATION (US) | 2023-06-22 | — | — | WO | disclosed |