Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29148098 | 0.93 | GPR183 (0.40) | CYP3A4HSD17B10CYP2C19USP2CYP1A2 | |
| SCHEMBL30694298 | 0.93 | GPR183 (0.40) | CYP3A4HSD17B10CYP2C19USP2CYP1A2 | |
| SCHEMBL22454337 | 0.81 | CYP3A4 (0.47) | CYP3A4HSD17B10CYP2C19USP2ALDH1A1 | |
| SCHEMBL20231722 | 0.81 | HSD17B10 (0.47) | CYP3A4HSD17B10CYP2C19USP2ALDH1A1 | |
| SCHEMBL22297612 | 0.80 | HSD17B10 (0.47) | CYP3A4HSD17B10CYP2C19USP2ALDH1A1 | |
| SCHEMBL31155509 | 0.79 | CYP3A4 (0.47) | CYP3A4HSD17B10CYP2C19USP2ALDH1A1 | |
| SCHEMBL31155546 | 0.78 | HSD17B10 (0.47) | CYP3A4HSD17B10CYP2C19USP2ALDH1A1 | |
| SCHEMBL25313895 | 0.78 | CYP3A4 (0.58) | CYP3A4HSD17B10CYP2C19USP2ALDH1A1 | |
| SCHEMBL30702599 | 0.76 | SIRT6 (0.35) | CYP3A4HSD17B10CYP2C19USP2ALDH1A1 | |
| SCHEMBL31568634 | 0.75 | ALDH1A1 (0.40) | ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4541795-A1 | AROMATIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF IN PREPARATION OF ESTROGEN RECEPTOR DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2025-04-23 | — | — | EP | disclosed |