Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 16/20 | 0.52 |
| ▸ | THRA | P10827 | 15/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381860 | 0.87 | THRB (0.53) | THRBTHRACNR2 | |
| SCHEMBL3160661 | 0.85 | THRB (0.54) | THRBTHRA | |
| SCHEMBL3146961 | 0.85 | THRB (0.53) | THRBTHRA | |
| SCHEMBL281956 | 0.80 | THRB (0.77) | THRBTHRA | |
| SCHEMBL13381858 | 0.78 | THRB (0.55) | THRBTHRA | |
| SCHEMBL4963877 | 0.78 | THRB (0.64) | THRBTHRA | |
| SCHEMBL13381823 | 0.77 | THRB (0.54) | THRBTHRA | |
| SCHEMBL13044695 | 0.77 | THRB (0.52) | THRBTHRA | |
| SCHEMBL13381857 | 0.77 | THRB (0.54) | THRBTHRA | |
| SCHEMBL3156352 | 0.76 | THRA (0.54) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081634-A1 | Novel Phosphorus-Containing Thyromimetics | METABASIS THERAPEUTICS, INC. (US) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081634-A1 | Novel Phosphorus-Containing Thyromimetics | PYGL, THRA, THOP1 | THRB 6/4885THRA 2/4885CNR2 3067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.