SCHEMBL31574489

SCHEMBL31574489

CC(=O)c1ccc(-c2ccc3[nH]ccc3c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.60
MAOA P21397 1/20 0.59
NPC1 O15118 1/20 0.59
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
HDAC2 Q92769 1/20 0.54
MAPT P10636 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C19 P33261 1/20 0.53
RAB9A P51151 1/20 0.53
AR P10275 1/20 0.52
FASN P49327 1/20 0.52
ENPP2 Q13822 1/20 0.48
CTNNB1 P35222 1/20 0.48
WNT3A P56704 1/20 0.48
CYP17A1 P05093 1/20 0.48
CYP11B1 P15538 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19391065 1.00 PTGS2 (0.60) PTGS2MAOANPC1CA12CA1
SCHEMBL7087653 0.87 MAP4K4 (0.62) PTGS2MAOANPC1CA12CA1
SCHEMBL5661439 0.87 KDM4E (0.57) PTGS2MAOAMAPTENPP2HSD17B1
SCHEMBL120471 0.86 MAOA (0.66) MAOANPC1MAPTCYP1A2CYP3A4
SCHEMBL27583671 0.85 NPC1 (0.66) PTGS2NPC1CA12CA1CA2
SCHEMBL19391117 0.83 PTGS2 (0.52) PTGS2MAOANPC1CA12CA1
SCHEMBL22220936 0.83 PTGS2 (0.56) PTGS2NPC1CA12CA1CA2
SCHEMBL7084698 0.83 PTGS2 (0.56) PTGS2MAOANPC1CA12CA1
SCHEMBL14348335 0.82 PTGS2 (0.56) PTGS2MAOANPC1CA12CA1
SCHEMBL5850255 0.80 NPC1 (0.79) PTGS2NPC1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998272-A Methanogen inhibitors 阿格里泽伦茨有限合伙公司 2025-05-13 CN disclosed