Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.55 |
| ▸ | WNT3A | P56704 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | FASN | P49327 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28752855 | 0.88 | ALDH1A1 (0.53) | PTGS2CTNNB1WNT3AMAPTSMN1; SMN2 | |
| SCHEMBL28790574 | 0.87 | CTNNB1 (0.65) | CTNNB1WNT3AMAPTCYP1A2CYP3A4 | |
| SCHEMBL19391065 | 0.83 | PTGS2 (0.60) | PTGS2CTNNB1WNT3ANPC1MAPT | |
| SCHEMBL31574489 | 0.83 | PTGS2 (0.60) | PTGS2CTNNB1WNT3ANPC1MAPT | |
| SCHEMBL27583671 | 0.81 | NPC1 (0.66) | PTGS2CTNNB1WNT3ANPC1MAPT | |
| SCHEMBL22220936 | 0.79 | PTGS2 (0.56) | PTGS2CTNNB1WNT3ANPC1MAPT | |
| SCHEMBL17742727 | 0.78 | ALDH1A1 (0.64) | CTNNB1WNT3AMAPTSMN1; SMN2HDAC2 | |
| SCHEMBL10389933 | 0.76 | SMN1; SMN2 (0.83) | NPC1MAPTSMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL5850255 | 0.76 | NPC1 (0.79) | PTGS2NPC1CA12CA1CA2 | |
| SCHEMBL31504065 | 0.76 | NPC1 (0.62) | PTGS2NPC1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | 4SC AG (DE) | 2003-10-30 | — | — | US | disclosed |
| WO-2003074047-A1 | INDOLE DERIVATIVES AS MODULATORS OF POTASSIUM CHANNELS | 4SC AG (DE) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | HCN3, KCNN3, KCNN1 | PTGS2 3620/4885CTNNB1 1958/4885WNT3A 2149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.