SCHEMBL31575348

SCHEMBL31575348

C[C@H](c1ccc(Cl)cc1)C(C(N)=O)[C@@H]1CCCN1C

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.43
CHRNA5 P30532 1/20 0.43
CHRNA7 P36544 1/20 0.43
CHRNA4 P43681 1/20 0.43
DPP4 P27487 1/20 0.42
DPP7 Q9UHL4 1/20 0.42
GLA P06280 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CHRNB4 P30926 4/20 0.39
CHRNA3 P32297 4/20 0.39
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31575359 1.00 CHRNB2 (0.43) CHRNB2CHRNA5CHRNA7CHRNA4DPP4
SCHEMBL30166180 0.96 SLC6A2 (0.44) CHRNB2CHRNA5CHRNA7CHRNA4DPP4
SCHEMBL31575328 0.96 SLC6A2 (0.44) CHRNB2CHRNA5CHRNA7CHRNA4DPP4
SCHEMBL31575334 0.87 DPP4 (0.46) DPP4DPP7CHRNB4CHRNA3
SCHEMBL31575321 0.87 DPP4 (0.46) DPP4DPP7CHRNB4CHRNA3
SCHEMBL31575342 0.84 DPP4 (0.45) DPP4DPP7SLC6A2SLC6A4SLC6A3
SCHEMBL10112661 0.80 SLC6A2 (0.44) CHRNB2CHRNA5CHRNA7CHRNA4SLC6A2
SCHEMBL7870941 0.78 SLC6A3 (0.46) CHRNB2CHRNA4SLC6A3CHRNB4CHRNA3
SCHEMBL3825931 0.76 SLC6A2 (0.47) CHRNB2CHRNA5CHRNA7CHRNA4SLC6A2
SCHEMBL14193555 0.76 CHRNB4 (0.41) CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115380030-B N-heteroarylalkyl-2- (heterocyclyl and heterocyclylmethyl) acetamide derivatives as SSTR4 agonists 武田药品工业株式会社 2025-05-16 CN disclosed