Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 8/20 | 0.46 |
| ▸ | CA2 | P00918 | 8/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18007612 | 0.73 | KDM1A (0.46) | L3MBTL1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL25233234 | 0.69 | GRM4 (0.48) | PTGS2ALDH1A1HSD17B10TDP1DRD2 | |
| SCHEMBL2819653 | 0.68 | P2RX7 (1.00) | P2RX7NOTUMMAOAL3MBTL1CA1 | |
| SCHEMBL23153549 | 0.68 | ESRRA (0.59) | P2RX7NOTUMMAOAL3MBTL1CA1 | |
| SCHEMBL14605595 | 0.68 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1DRD2DRD4 | |
| SCHEMBL6030190 | 0.67 | NOTUM (0.58) | P2RX7NOTUMMAOAL3MBTL1CA1 | |
| SCHEMBL12959177 | 0.67 | P2RX7 (0.55) | P2RX7NOTUMMAOAL3MBTL1CA1 | |
| SCHEMBL23028378 | 0.67 | NOTUM (0.58) | P2RX7NOTUMMAOAL3MBTL1ESRRA | |
| SCHEMBL17039112 | 0.67 | P2RX7 (0.55) | P2RX7NOTUMMAOAL3MBTL1CA1 | |
| SCHEMBL2629357 | 0.67 | P2RX7 (0.55) | P2RX7NOTUMMAOAL3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250161281-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. | 2025-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250161281-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | EBPL, EBP, CREBBP | P2RX7 4826/4885NOTUM 1891/4885MAOA 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.