Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31583269 | 0.76 | L3MBTL1 (0.34) | DDB1CRBNLMNATP53THRB | |
| SCHEMBL31582837 | 0.74 | MAPK13 (0.36) | DDB1CRBNCYP1A2GRM4BRD4 | |
| SCHEMBL13106346 | 0.74 | LMNA (0.43) | DDB1CRBNLMNATP53THRB | |
| SCHEMBL15995629 | 0.73 | LMNA (0.34) | DDB1CRBNLMNATP53THRB | |
| SCHEMBL30706223 | 0.73 | LMNA (0.37) | DDB1CRBNPARP1LMNATP53 | |
| SCHEMBL15995385 | 0.73 | DDB1 (0.38) | DDB1CRBNPDE10ALMNATP53 | |
| SCHEMBL26637934 | 0.73 | LMNA (0.37) | DDB1CRBNPARP1LMNATP53 | |
| SCHEMBL27140925 | 0.73 | JAK2 (0.35) | DDB1CRBNLMNATP53THRB | |
| SCHEMBL15995754 | 0.70 | LMNA (0.33) | DDB1CRBNLMNATP53THRB | |
| SCHEMBL31582863 | 0.70 | ADORA3 (0.40) | DDB1CRBNLMNATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106644-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ALPHA-V BETA-1 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2025-05-22 | — | — | WO | disclosed |