Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706223 | 0.81 | LMNA (0.37) | L3MBTL1LMNATP53THRBTLR9 | |
| SCHEMBL13106346 | 0.79 | LMNA (0.43) | L3MBTL1LMNATP53THRBTLR9 | |
| SCHEMBL15995629 | 0.78 | LMNA (0.34) | L3MBTL1LMNATP53THRBTLR9 | |
| SCHEMBL15995385 | 0.78 | DDB1 (0.38) | L3MBTL1LMNATP53THRBTLR9 | |
| SCHEMBL15687253 | 0.76 | ESR1 (0.35) | L3MBTL1RXFP1LMNATP53ALDH1A1 | |
| SCHEMBL31582758 | 0.76 | DDB1 (0.43) | L3MBTL1LMNATP53THRBTLR9 | |
| SCHEMBL14077453 | 0.75 | L3MBTL1 (0.41) | L3MBTL1LMNATP53THRBTLR9 | |
| SCHEMBL7572834 | 0.75 | KMT2A (0.37) | L3MBTL1RXFP1LMNAHTT | |
| SCHEMBL31582651 | 0.75 | LMNA (0.35) | L3MBTL1LMNATP53THRBTLR9 | |
| SCHEMBL31582863 | 0.75 | ADORA3 (0.40) | L3MBTL1LMNATP53THRBTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106644-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ALPHA-V BETA-1 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2025-05-22 | — | — | WO | disclosed |