Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.53 |
| ▸ | CTSK | P43235 | 9/20 | 0.53 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24502886 | 1.00 | CTSS (0.53) | CTSSCTSKCTSBKLK5PTPN1 | |
| SCHEMBL31584535 | 0.85 | CTSS (0.69) | CTSSCTSKCTSBKLK5PTPN1 | |
| SCHEMBL5630007 | 0.85 | CTSS (0.69) | CTSSCTSKCTSBKLK5PTPN1 | |
| SCHEMBL15808276 | 0.84 | CTSS (0.56) | CTSSCTSKCTSBKLK5PTPN1 | |
| SCHEMBL31584143 | 0.83 | CTSB (0.46) | CTSSCTSKCTSBPTPN1ROCK2 | |
| SCHEMBL29679126 | 0.83 | CTSL (0.58) | CTSSCTSKCTSBCTSLROCK2 | |
| SCHEMBL29679181 | 0.83 | CTSL (0.58) | CTSSCTSKCTSBCTSLROCK2 | |
| SCHEMBL31584126 | 0.83 | CTSS (0.45) | CTSSCTSKCTSBPTPN1ROCK2 | |
| SCHEMBL13538229 | 0.82 | KLK5 (0.57) | CTSSCTSKCTSBKLK5ITGB3 | |
| SCHEMBL13541200 | 0.82 | KLK5 (0.57) | CTSSCTSKCTSBKLK5ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106939-A1 | CONJUGATES TARGETING FIBROBLAST ACTIVATION PROTEIN AND USES THEREOF | Praxis Biotech LLC (US) | 2025-05-22 | — | — | WO | disclosed |