Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 7/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | DUT | P33316 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25395276 | 0.78 | CNR2 (0.37) | TNFCNR2DUTALDH1A1HDAC6 | |
| SCHEMBL31584367 | 0.78 | TNF (0.37) | TNFCNR2DUTKDM4EALDH1A1 | |
| SCHEMBL25394242 | 0.75 | HDAC8 (0.39) | TNFCNR2ALDH1A1HDAC6HDAC3 | |
| SCHEMBL25393843 | 0.74 | SIGMAR1 (0.38) | TNFDUT | |
| SCHEMBL31688997 | 0.74 | CNR1 (0.46) | CNR2KDM4EALDH1A1CNR1 | |
| SCHEMBL31584352 | 0.73 | FPR2 (0.41) | TNFCNR2DUT | |
| SCHEMBL25392985 | 0.71 | SIGMAR1 (0.38) | CNR2DUTHDAC6HDAC3HDAC1 | |
| SCHEMBL22114505 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1 | |
| SCHEMBL25391946 | 0.70 | ALDH1A1 (0.35) | CNR2KDM4EALDH1A1HDAC6HDAC3 | |
| SCHEMBL12638925 | 0.70 | KMT2A (0.61) | ALDH1A1HDAC6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106863-A1 | LACTAM DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-05-22 | — | — | WO | disclosed |