Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | FDPS | P14324 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | FURIN | P09958 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31585229 | 0.77 | ENPP3 (0.39) | HDAC4NAAASCN9AADRB2ADRB1 | |
| SCHEMBL31585545 | 0.73 | NAAA (0.39) | NAAASCN9AGPR119 | |
| SCHEMBL28159410 | 0.71 | SCN9A (0.51) | SCN9A | |
| SCHEMBL1186172 | 0.68 | ESR1 (0.46) | HDAC4NAAASCN9AAR | |
| SCHEMBL1646055 | 0.68 | HDAC4 (0.44) | HDAC4SCN9A | |
| SCHEMBL26675778 | 0.68 | TDP1 (0.42) | FURIN | |
| SCHEMBL26826953 | 0.68 | TDP1 (0.42) | FURIN | |
| SCHEMBL26675785 | 0.68 | TDP1 (0.42) | FURIN | |
| SCHEMBL26098186 | 0.67 | GRIN1 (0.43) | CHRM1FURIN | |
| SCHEMBL31585029 | 0.67 | EPHX2 (0.44) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106362-A1 | RIPK1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2025-05-22 | — | — | WO | disclosed |