Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007463 | 0.84 | ESR1 (0.57) | ESR1MAPTALDH1A1POLBHPGD | |
| SCHEMBL5836419 | 0.78 | SCN9A (0.43) | ALDH1A1HDAC4MEN1KMT2ANPC1 | |
| SCHEMBL1646055 | 0.78 | HDAC4 (0.44) | MAPTALDH1A1HPGDHSD17B10HDAC4 | |
| SCHEMBL9288053 | 0.78 | ENPP3 (0.47) | MAPTALDH1A1POLBHPGDHDAC4 | |
| SCHEMBL5999068 | 0.78 | HDAC4 (0.44) | MAPTALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL16058716 | 0.78 | NAAA (0.43) | HDAC4NAAASCN9AMKNK1MKNK2 | |
| SCHEMBL4751198 | 0.76 | HSD17B1 (0.58) | SCN9AHSD17B1HSD17B2 | |
| SCHEMBL4765377 | 0.76 | HDAC4 (0.50) | ALDH1A1POLBHPGDHDAC4NPC1 | |
| SCHEMBL3193030 | 0.76 | LMNA (0.43) | MAPTHDAC4NAAANPC1RAB9A | |
| SCHEMBL1655655 | 0.75 | P4HA1 (0.32) | ESR1HDAC4SCN9AHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890923-B2 | Compounds | ASTRAZENECA AB (SE) | 2005-05-10 | — | — | US | claimed |
| US-20040122028-A1 | Novel compounds | ASTRAZENECA AB (SE) | 2004-06-24 | — | — | US | claimed |
| WO-2025106362-A1 | RIPK1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2025-05-22 | — | — | WO | disclosed |
| WO-2025070747-A1 | METHOD FOR MEASURING ANTIGEN CONTAINED IN TEST SAMPLE, AND KIT FOR MEASURING HUMAN CHORIONIC GONADOTROPIN OR ESTRADIOL | 富士フイルム株式会社 | 2025-04-03 | — | — | WO | disclosed |
| EP-4325210-A1 | COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE | FUJIFILM Corporation (JP) | 2024-02-21 | — | — | EP | disclosed |
| US-20240043742-A1 | COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE | FUJIFILM CORPORATION (JP) | 2024-02-08 | — | — | US | disclosed |
| WO-2022220288-A1 | COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE | 富士フイルム株式会社 | 2022-10-20 | — | — | WO | disclosed |
| EP-3366750-B1 | STABILIZER AND STABILIZATION METHOD | FUJIFILM WAKO PURE CHEMICAL CORP (JP) | 2021-07-21 | — | — | EP | disclosed |
| US-10961185-B2 | Stabilizer and stabilization method | FUJIFILM WAKO PURE CHEMICAL CHEMICAL CORPORATION (JP) | 2021-03-30 | — | — | US | disclosed |
| CN-108138047-B | Stabilizer and stabilization method | 富士胶片和光纯药株式会社 | 2021-02-09 | — | — | CN | disclosed |
| CN-105315319-B | Hepatitis C virus inhibitor and application thereof | 南京圣和药业股份有限公司 | 2020-11-20 | — | — | CN | disclosed |
| US-20030166686-A1 | Beta3 adrenergic receptor agonist crystal forms, processes for the production thereof, and uses thereof | PFIZER INC. | 2003-09-04 | — | — | US | disclosed |
| WO-2003072573-A1 | CRYSTAL FORMS OF (R)-2-(2-(4-OXAZOL-4-YL-PHENOXY)-ETHYLAMINO)-1-PYRIDIN-3-YL-ETHANOL | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | disclosed |
| EP-0384271-B1 | Method for enhancement of chemiluminescence | WAKO PURE CHEM IND LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5106732-A | Using oxazole or thiazole derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0384271-A2 | Method for enhancement of chemiluminescence | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| US-4005201-A | DIURETICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961185-B2 | Stabilizer and stabilization method | H1-0, H1-2, H1-4 | ESR1 3595/4885MAPT 2821/4885ALDH1A1 993/4885 |
| US-20040122028-A1 | Novel compounds | DPYD, TYMS, TYMP | ESR1 3579/4885MAPT 4073/4885ALDH1A1 284/4885 |
| US-20030166686-A1 | Beta3 adrenergic receptor agonist crystal forms, processes for the production thereof, and uses thereof | ADRB3, ADRB1, ADRB2 | ESR1 2546/4885MAPT 1416/4885ALDH1A1 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.