Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31585093 | 0.76 | CYP2D6 (0.48) | NAAACYP2D6MEN1KMT2AMAPT | |
| SCHEMBL11024377 | 0.74 | CYP2D6 (0.58) | NAAACYP2D6CA12CA2MEN1 | |
| SCHEMBL14780313 | 0.74 | CYP2D6 (0.58) | NAAACYP2D6CA12CA2MEN1 | |
| SCHEMBL11024375 | 0.74 | CYP2D6 (0.58) | NAAACYP2D6CA12CA2MEN1 | |
| SCHEMBL31585035 | 0.73 | HDAC4 (0.38) | NAAASCN9AGPR119 | |
| SCHEMBL31308763 | 0.73 | ACHE (0.46) | NAAACYP2D6CA2MEN1KMT2A | |
| SCHEMBL1032222 | 0.71 | SCN9A (0.39) | NAAASCN9ACA12CA2EDNRB | |
| SCHEMBL9288053 | 0.71 | ENPP3 (0.47) | SCN9AMEN1KMT2AMAPTEDNRB | |
| SCHEMBL31565470 | 0.69 | CA12 (0.44) | NAAACYP2D6CA12CA2MEN1 | |
| SCHEMBL25417201 | 0.68 | CYP2D6 (0.52) | NAAACYP2D6CA12CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106362-A1 | RIPK1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2025-05-22 | — | — | WO | disclosed |