Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3168102 | 0.75 | CHRNB2 (0.49) | KMT2AL3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9996420 | 0.71 | KMT2A (0.48) | KMT2AL3MBTL1POLBMAPK1CYP3A4 | |
| SCHEMBL9996712 | 0.71 | TDP1 (0.45) | KMT2ATDP1L3MBTL1POLBMAPK1 | |
| SCHEMBL2401814 | 0.70 | P2RX7 (0.44) | KMT2ATP53CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL22694581 | 0.69 | TP53 (0.36) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL23362392 | 0.68 | HTT (0.48) | KMT2ATDP1TP53POLBMAPK1 | |
| SCHEMBL18906051 | 0.68 | KDM5A (0.56) | KMT2AL3MBTL1KDM4CKDM4EKDM5A | |
| SCHEMBL7511801 | 0.67 | CYP2C9 (0.46) | KMT2AL3MBTL1POLBCHRNB2CHRNB4 | |
| SCHEMBL11044495 | 0.67 | KMT2A (0.62) | KMT2ATDP1L3MBTL1ESR1TP53 | |
| SCHEMBL7880818 | 0.66 | FABP1 (0.65) | KMT2ATP53POLBMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010018601-A | HETEROCYCLIC COMPOUND, METHOD FOR PRODUCING THE SAME AND USE THEREOF | NISHIO TETSUYA | 2010-01-28 | — | — | JP | disclosed |