Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494091 | 0.79 | HIF1A (0.66) | HIF1AKDM4CALDH1A1KDM4EGAA | |
| SCHEMBL3158685 | 0.75 | KMT2A (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4C | |
| SCHEMBL18906051 | 0.75 | KDM5A (0.56) | HIF1AKDM4CKDM4EFOLH1KDM5B | |
| SCHEMBL7880818 | 0.75 | FABP1 (0.65) | HIF1AALDH1A1HPGDKDM4ECYP3A4 | |
| SCHEMBL9996420 | 0.74 | KMT2A (0.48) | KDM4CALDH1A1HPGDCYP3A4CYP2D6 | |
| SCHEMBL14830351 | 0.73 | HIF1A (0.81) | HIF1AKDM4CALDH1A1FOLH1NOX4 | |
| SCHEMBL27648140 | 0.72 | ALDH1A1 (0.49) | HIF1AKDM4CALDH1A1KDM4EGAA | |
| SCHEMBL9567555 | 0.72 | HPGD (0.63) | HIF1AKDM4CALDH1A1HPGDKDM4E | |
| SCHEMBL2401814 | 0.72 | P2RX7 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4CYP3A4 | |
| SCHEMBL30879601 | 0.70 | HIF1A (0.57) | HIF1AALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010018601-A | HETEROCYCLIC COMPOUND, METHOD FOR PRODUCING THE SAME AND USE THEREOF | NISHIO TETSUYA | 2010-01-28 | — | — | JP | disclosed |