SCHEMBL31589999

SCHEMBL31589999

O=C(O)N1CCN(c2ccc(-c3ccc(Cl)cc3F)cn2)CC1

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 9/20 0.63
CNR2 P34972 5/20 0.49
FASN P49327 1/20 0.47
HSD17B10 Q99714 1/20 0.44
TDO2 P48775 1/20 0.44
CNR1 P21554 1/20 0.43
ME2 P23368 1/20 0.42
ME1 P48163 1/20 0.42
ME3 Q16798 1/20 0.42
RET P07949 1/20 0.42
PANK3 Q9H999 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31590771 0.89 MGLL (0.61) MGLLCNR2TDO2ME2ME1
SCHEMBL5236075 0.88 CNR2 (0.54) MGLLCNR2HSD17B10CNR1ME2
SCHEMBL31590682 0.85 MGLL (0.64) MGLLFASNHSD17B10
SCHEMBL5233345 0.85 CNR2 (0.51) MGLLCNR2HSD17B10CNR1RET
SCHEMBL31589940 0.84 MGLL (0.63) MGLLCNR2RET
SCHEMBL5235945 0.83 MGLL (0.57) MGLLCNR2ME2ME1ME3
SCHEMBL5237235 0.81 MGLL (0.53) MGLLCNR2CNR1ME2ME1
SCHEMBL31589359 0.81 MGLL (0.53) MGLLCNR2ME2ME1ME3
SCHEMBL16397570 0.80 PANK3 (0.57) CNR2ME2ME1ME3PANK3
SCHEMBL31589343 0.80 CNR2 (0.44) MGLLCNR2TDO2CNR1RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025108106-A1 COMPOUND CONTAINING QUINOLINONE SKELETON AND USE THEREOF 中国药科大学 2025-05-30 WO disclosed
CN-120040415-A Compound containing quinolinone skeleton and application thereof 中国药科大学 2025-05-27 CN disclosed