Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.51 |
| ▸ | MGLL | Q99685 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236075 | 0.96 | CNR2 (0.54) | CNR2MGLLCNR1HSD17B10RET | |
| SCHEMBL5237235 | 0.88 | MGLL (0.53) | CNR2MGLLCNR1L3MBTL1RAB9A | |
| SCHEMBL31589999 | 0.85 | MGLL (0.63) | CNR2MGLLCNR1HSD17B10RET | |
| SCHEMBL5235945 | 0.82 | MGLL (0.57) | CNR2MGLLL3MBTL1RAB9A | |
| SCHEMBL31589359 | 0.80 | MGLL (0.53) | CNR2MGLLRET | |
| SCHEMBL5236215 | 0.80 | FAAH (0.43) | CNR2MGLLCNR1RETMEN1 | |
| SCHEMBL16397570 | 0.79 | PANK3 (0.57) | CNR2RAB9A | |
| SCHEMBL31589932 | 0.79 | CNR2 (0.64) | CNR2MGLLCNR1RET | |
| SCHEMBL5231208 | 0.79 | SRD5A2 (0.50) | CNR1MEN1RAB9AKMT2A | |
| SCHEMBL31589940 | 0.79 | MGLL (0.63) | CNR2MGLLRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |