Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.53 |
| ▸ | CNR2 | P34972 | 4/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | ME2 | P23368 | 2/20 | 0.47 |
| ▸ | ME1 | P48163 | 2/20 | 0.47 |
| ▸ | ME3 | Q16798 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.44 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235945 | 0.95 | MGLL (0.57) | MGLLCNR2EGLN1ME2ME1 | |
| SCHEMBL5233345 | 0.88 | CNR2 (0.51) | MGLLCNR2CNR1RAB9AL3MBTL1 | |
| SCHEMBL5235836 | 0.86 | CNR2 (0.63) | MGLLCNR2EGLN1CNR1ADK | |
| SCHEMBL31589359 | 0.84 | MGLL (0.53) | MGLLCNR2EGLN1ME2ME1 | |
| SCHEMBL5234185 | 0.84 | KDM4E (0.59) | MGLLCNR2SLC6A7KDM4EPOLB | |
| SCHEMBL5238882 | 0.84 | EGLN1 (0.51) | MGLLEGLN1ME2ME1ME3 | |
| SCHEMBL3442393 | 0.84 | MGLL (0.58) | MGLLCNR2ME2ME1ME3 | |
| SCHEMBL5236075 | 0.84 | CNR2 (0.54) | MGLLCNR2ME2ME1ME3 | |
| SCHEMBL16397570 | 0.83 | PANK3 (0.57) | CNR2ME2ME1ME3PANK3 | |
| SCHEMBL31589999 | 0.81 | MGLL (0.63) | MGLLCNR2ME2ME1ME3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |