Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 11/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739113 | 0.87 | KLKB1 (0.45) | KLKB1ALDH1A1SMN1; SMN2F2CYP3A4 | |
| SCHEMBL30739420 | 0.79 | NPC1 (0.40) | ALDH1A1LMNASMN1; SMN2CYP3A4POLB | |
| SCHEMBL31591085 | 0.78 | TSHR (0.46) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30739078 | 0.78 | KLKB1 (0.57) | KLKB1 | |
| SCHEMBL30739314 | 0.76 | KLKB1 (0.42) | KLKB1EPHX2NR1H4 | |
| SCHEMBL30739059 | 0.76 | KLKB1 (0.47) | KLKB1F2CYP3A4GPR142 | |
| SCHEMBL30739076 | 0.70 | KLKB1 (0.56) | KLKB1 | |
| SCHEMBL30739114 | 0.70 | KLKB1 (0.46) | KLKB1F2 | |
| SCHEMBL368793 | 0.67 | NPBWR1 (0.45) | POLB | |
| SCHEMBL30739057 | 0.67 | NPC1 (0.42) | ALDH1A1LMNASMN1; SMN2CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561993-A1 | INHIBITORS OF PLASMA KALLIKREIN | Rezolute, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024025907-A1 | INHIBITORS OF PLASMA KALLIKREIN | REZOLUTE, INC. (US) | 2024-02-01 | — | — | WO | disclosed |