Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31591941 | 1.00 | HCAR3 (0.50) | HCAR3RORCTP53NPC1RAB9A | |
| SCHEMBL31591981 | 1.00 | HCAR3 (0.50) | HCAR3RORCTP53NPC1RAB9A | |
| SCHEMBL31591948 | 0.91 | RORC (0.45) | HCAR3RORCTP53NPC1RAB9A | |
| SCHEMBL31591951 | 0.84 | HCAR3 (0.53) | HCAR3TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15992318 | 0.78 | PPARG (0.48) | HCAR3TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15992042 | 0.78 | RAB9A (0.54) | HCAR3TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15992196 | 0.76 | PPARG (0.49) | HCAR3TP53HPGDLMNA | |
| SCHEMBL15991817 | 0.76 | PPARG (0.49) | HCAR3TP53HPGDLMNA | |
| SCHEMBL31591949 | 0.75 | KMT2A (0.48) | HCAR3TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7721164 | 0.72 | HCAR3 (0.72) | HCAR3NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912563-B | Benzo five-membered nitrogen heterocyclic compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2025-05-27 | — | — | CN | disclosed |