Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | APP | P05067 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31591998 | 0.91 | RORC (0.62) | RORCCCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL31591984 | 0.85 | MAPT (0.61) | RORCCCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL31591996 | 0.83 | RORC (0.49) | RORCCCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL31592004 | 0.82 | RORC (0.60) | RORCCCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL31592002 | 0.78 | MAPT (0.53) | RORCCCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL10311768 | 0.78 | RORC (0.71) | RORCCCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL31591973 | 0.77 | RORC (0.59) | RORCCCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL25307017 | 0.76 | ALDH1A1 (0.78) | RORCMAPTAPPGAAKDM4E | |
| SCHEMBL1986906 | 0.76 | NFE2L2 (0.60) | RORCMAPTAPPGAAKDM4E | |
| SCHEMBL1986908 | 0.76 | NFE2L2 (0.60) | RORCMAPTAPPGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912563-B | Benzo five-membered nitrogen heterocyclic compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2025-05-27 | — | — | CN | disclosed |