Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146178 | 0.85 | KDM4E (0.51) | AKR1C3AKR1C2KDM4EAPAF1POLB | |
| SCHEMBL3157543 | 0.81 | PTGER1 (0.48) | AKR1C3AKR1C2KDM4EAPAF1POLB | |
| SCHEMBL6906723 | 0.80 | CRHR1 (0.43) | AKR1C3AKR1C2MAPTALOX5 | |
| SCHEMBL25846959 | 0.76 | CTNNB1 (0.59) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL6907446 | 0.76 | CTNNB1 (0.59) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL16017641 | 0.76 | CTNNB1 (0.59) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL28690577 | 0.76 | AKR1C3 (0.59) | AKR1C3AKR1C2KDM4EPPARGPPARA | |
| SCHEMBL3142514 | 0.75 | KDM4E (0.49) | AKR1C3AKR1C2KDM4EAPAF1POLB | |
| SCHEMBL22888380 | 0.74 | AKR1C3 (0.48) | AKR1C3AKR1C2KDM4EMAPTALOX5 | |
| SCHEMBL3141425 | 0.73 | PTGER1 (0.54) | KDM4EAPAF1POLBMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270614-B1 | Copolymers containing propylene and alpha-olefin comonomer | BASELL POLYOLEFINE GMBH (DE) | 2010-01-27 | — | — | EP | disclosed |
| US-6787618-B1 | TRANSPARENT, STIFF MOLDING MATERIALS; IMPACT TOUGHNESS; FOOD PACKAGING | BASELL POLYPROPYLEN GMBH (DE) | 2004-09-07 | — | — | US | disclosed |
| EP-0776913-B1 | High molecular weight copolymers | BASELL POLYOLEFINE GMBH (DE) | 2004-02-04 | — | — | EP | disclosed |
| EP-1270614-A2 | Copolymers containing propylene and alpha-olefin comonomer | Basell Polyolefine GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6057408-A | CATALYTIC ADDITION COPOLYMERIZATION OF PROPYLENE WITH ETHYLENE OR OLEFIN | TARGOR GMBH (DE) | 2000-05-02 | — | — | US | disclosed |
| EP-0776913-A2 | High molecular weight copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-04 | — | — | EP | disclosed |