Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3159240 | 0.80 | AKR1C3 (0.51) | AKR1C3AKR1C2ALOX5MAPT | |
| SCHEMBL3101185 | 0.78 | CYP1A2 (0.45) | GAACYP1A2CYP2D6MAPT | |
| SCHEMBL31517086 | 0.78 | CYP1A2 (0.45) | GAACYP1A2CYP2D6MAPT | |
| SCHEMBL28691596 | 0.78 | CRHR1 (0.50) | CRHR1AKR1C3AKR1C2KIF11GAA | |
| SCHEMBL22888380 | 0.78 | AKR1C3 (0.48) | CRHR1AKR1C3AKR1C2KIF11GAA | |
| SCHEMBL3139862 | 0.76 | METAP2 (0.42) | CRHR1AKR1C3AKR1C2KIF11LMNA | |
| SCHEMBL16075900 | 0.75 | AKR1C3 (0.70) | CRHR1AKR1C3AKR1C2KIF11GAA | |
| SCHEMBL9179432 | 0.75 | UGT2B7 (0.44) | CRHR1AKR1C3AKR1C2KIF11GAA | |
| SCHEMBL27764964 | 0.72 | LMNA (0.44) | KIF11GAALMNANPC1MAPT | |
| SCHEMBL6909828 | 0.70 | HPRT1 (0.52) | LMNACYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787618-B1 | TRANSPARENT, STIFF MOLDING MATERIALS; IMPACT TOUGHNESS; FOOD PACKAGING | BASELL POLYPROPYLEN GMBH (DE) | 2004-09-07 | — | — | US | disclosed |
| EP-0776913-B1 | High molecular weight copolymers | BASELL POLYOLEFINE GMBH (DE) | 2004-02-04 | — | — | EP | disclosed |
| EP-1270614-A2 | Copolymers containing propylene and alpha-olefin comonomer | Basell Polyolefine GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6057408-A | CATALYTIC ADDITION COPOLYMERIZATION OF PROPYLENE WITH ETHYLENE OR OLEFIN | TARGOR GMBH (DE) | 2000-05-02 | — | — | US | disclosed |
| EP-0776913-A2 | High molecular weight copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-04 | — | — | EP | disclosed |