Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.33 |
| ▸ | CKS1B | P61024 | 2/20 | 0.32 |
| ▸ | SKP1 | P63208 | 2/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31597669 | 0.84 | PREP (0.34) | HDAC1MEN1KMT2AGPR119CKS1B | |
| SCHEMBL31598413 | 0.81 | TRPV3 (0.36) | MEN1KMT2AGPR119LMNANPSR1 | |
| SCHEMBL30745382 | 0.76 | MEN1 (0.36) | MEN1KMT2AGPR119CKS1BSKP1 | |
| SCHEMBL31597791 | 0.74 | LMNA (0.35) | MEN1KMT2AGPR119LMNANPSR1 | |
| SCHEMBL31598218 | 0.72 | JAK1 (0.35) | MEN1KMT2AGPR119JAK2JAK1 | |
| SCHEMBL17747329 | 0.72 | TACR1 (0.41) | HDAC1MEN1KMT2ANPSR1 | |
| SCHEMBL30358529 | 0.71 | NTRK1 (0.39) | ALKGPR119JAK2JAK1 | |
| SCHEMBL30358526 | 0.71 | NTRK1 (0.39) | ALKGPR119JAK2JAK1 | |
| SCHEMBL30745353 | 0.71 | TRPV3 (0.44) | MEN1KMT2AGPR119LMNAGRM5 | |
| SCHEMBL28977444 | 0.71 | NTRK1 (0.39) | ALKGPR119JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655695-B | Substituted furopyrimidine compounds as PDE1 inhibitors | 达特神经科学有限公司 | 2025-05-27 | — | — | CN | disclosed |