SCHEMBL16289399

SCHEMBL16289399

[CH2]c1cc(S(C)(=O)=O)ccn1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ROCK1 Q13464 2/20 0.39
▸ PTGS1 P23219 1/20 0.36
▸ PTGS2 P35354 1/20 0.36
▸ G6PD P11413 1/20 0.36
▸ IDE P14735 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ MET P08581 1/20 0.36
▸ ENPP2 Q13822 1/20 0.35
▸ CBFB Q13951 1/20 0.35
▸ RIPK2 O43353 2/20 0.35
▸ NR1H2 P55055 1/20 0.35
▸ NR1H3 Q13133 1/20 0.35
▸ RET P07949 1/20 0.35
▸ KDR P35968 1/20 0.35
▸ MAPK14 Q16539 1/20 0.35
▸ PKMYT1 Q99640 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13801171 0.77 UHRF1 (0.48) ROCK1PTGS2G6PDIDESMN1; SMN2
SCHEMBL10920036 0.77 ROCK1 (0.40) ROCK1PTGS1PTGS2G6PDIDE
SCHEMBL5700283 0.76 ROCK1 (0.37) ROCK1PTGS2G6PDIDESMN1; SMN2
SCHEMBL27496175 0.75 NOS3 (0.48) ROCK1G6PDIDE
SCHEMBL31599666 0.75 PTGS1 (0.39) ROCK1PTGS1PTGS2G6PDIDE
SCHEMBL1403910 0.75 PTGS1 (0.39) ROCK1PTGS1PTGS2G6PDIDE
SCHEMBL30700822 0.75 PTGS2 (0.46) ROCK1PTGS1PTGS2NR1H2NR1H3
SCHEMBL6883165 0.75 PTGS2 (0.46) ROCK1PTGS1PTGS2NR1H2NR1H3
SCHEMBL24453154 0.73 PRKCI (0.41) ROCK1SMN1; SMN2METNR1H2NR1H3
SCHEMBL5700227 0.73 HRH4 (0.41) ROCK1PTGS1PTGS2METENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 — — EP disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 — — EP disclosed
US-9854803-B2 Noxious arthropod control agent containing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 — — US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 — — US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 — — US disclosed
EP-3178323-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-06-14 — — EP disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 — — US disclosed
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-01 — — US disclosed
EP-2813492-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Co., Ltd (JP) 2014-12-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 ROCK1 1497/4885PTGS1 2269/4885PTGS2 1742/4885
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL RPS8, MT-CO2, ARG1 ROCK1 1655/4885PTGS1 1674/4885PTGS2 1886/4885
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND TRPA1, OPRM1, OPRL1 ROCK1 1766/4885PTGS1 269/4885PTGS2 372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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