Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31601048 | 0.84 | ESR2 (0.41) | GAAESR1ESR2ALDH1A1LMNA | |
| SCHEMBL30071553 | 0.81 | KMT2A (0.44) | GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL31600676 | 0.80 | FGFR1 (0.37) | GAAPOLBMGLLALDH1A1LMNA | |
| SCHEMBL31600264 | 0.77 | L3MBTL1 (0.40) | GAALMNA | |
| SCHEMBL31393107 | 0.76 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL14868960 | 0.69 | ALOX15 (0.45) | POLBLMNAHTTSMN1; SMN2MT-CO1 | |
| SCHEMBL31600583 | 0.69 | ALDH1A1 (0.33) | GAAESR1ESR2ALDH1A1LMNA | |
| SCHEMBL29220708 | 0.68 | GAA (0.46) | GAAESR1ESR2MGLLALDH1A1 | |
| SCHEMBL31600760 | 0.68 | NPC1 (0.34) | GAAESR1ESR2 | |
| SCHEMBL8356086 | 0.67 | NPC1 (0.41) | GAAESR1ESR2POLBMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |